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In today's competitive market, you need every advantage you can get. Fluidocap is a technological breakthrough that not only maximizes your product efficiency but also creates a unique brand differentiator. A technological breakthrough your marketing team will love as much as your customers.
Today, the most common way to deliver liquid formulation is through soft gelatin capsules. But soft gelatin capsule manufacturing has problems of cross contamination and is a messy production |
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process. More importantly, the process is an expensive and capital-intensive investment. No wonder most pharmaceutical companies prefer to outsource soft gelatin capsule production. Now, finally there is an alternative.
We present Fluidocap Technology - a cost effective, revolutionary new dosage delivery system. It involves filling of liquids and semi-solids in a hard capsule instead of a traditional soft gel capsule. It is processed with Flotfit capsules and Fluidocap F-40 & Fluidocap S-40, the liquid-filling and band-sealing machines. |
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| Advantages of Flotfit over Soft Gelatin |
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Flotfit allows manufacturers currently using soft gelatin to move to a more efficient and attractive delivery method with many advantages. |
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Does not utilize plasticizers that can lead to migration of drug into the capsule shell. |
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No moisture uptake and hence does not react with moisture-sensitive drugs. |
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Flotfit capsules have low permeability making them ideal for odorous drugs. |
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In-house production also facilitates adherence to quality standards and protection of intellectual property. |
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| Bioavailability |
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| Increase the efficiency of the drug in liquid formulation. The bioavailability of poorly water-soluble drugs can be significantly enhanced if formulated as a liquid in a Flotfit capsule. |
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| Take advantage of low melting point |
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| Formulations with low melting points often require high concentrations of excipients to avoid processing problems. The five step process required to manufacture a tablet can be reduced to a mix and fill process with Flotfit technology. Consumer acceptance is also enhanced due to smaller size of final dosage form. |
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| Content uniformity |
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| The liquid-filling process attains less than 3% fill weight variations with the drug uniformly dispersed in a liquid medium. |
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| Zero cross contamination |
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| You no longer have to install elaborate anti-contamination systems if your product line includes sensitive solid hormone and cytotoxic agents. |
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| Critical Stability |
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| Incorporating the drug into either a hydrophilic of lipophilic matrix can reduce a drug's sensitivity to moisture. |
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| Cost advantages of Flotfit over Soft Gelatin capsules |
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Capital Cost
Due to exorbitant capital cost and low return on investment, soft gelatin capsule operations often have to be outsourced. With Flotfit the investment cost is comparatively low. Maintenance is also minimal. |
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Variable Cost
Wastage of gelatin in soft gelatin capsule manufacturing is an expensive proposition. Flotfit negates this by ensuring substantial reduction in product and process wastage. |
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Other Costs
Space required for Flotfit operations is much lesser than that for soft gelatin. Production schedules are more streamlined due to less wastage. Flotfit capsules also have a much lower rejection rate. |
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| Advantages of band sealing |
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| Besides preventing leakage and reducing oxygen permeability, band sealing provides a tamper evident band, an effective way to keep counterfeiters away. |
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| Liquid filling and band sealing lab models for hard capsules |
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| To be a part of the continuous process of development in the pharmaceutical industry and to cater to the needs of R & D, Pam USA LLC has a lab range for liquid-filling and band-sealing specially designed for R & D applications. These machines are especially useful in development of liquid based formulation, which once developed can be scaled-up to commercial production without any change in the product developed. |
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